Which condition can lead to a thiamine deficiency?

Thiamine, also known as vitamin B1, plays a critical role in energy metabolism and the functioning of the nervous system. Long-term alcohol consumption is a well-documented condition that can lead to thiamine deficiency. Chronic alcohol intake often leads to poor nutritional intake and absorption issues. Alcohol can inhibit the absorption of thiamine in the intestines and can also lead to increased excretion of the vitamin through the kidneys. Additionally, individuals with alcohol use disorder may have a diet that lacks adequate vitamin B1, further exacerbating the deficiency. This interplay of reduced intake, impaired absorption, and increased loss contributes significantly to the risk of developing thiamine deficiency among those who consume alcohol over extended periods.

The other conditions listed, while they may affect overall health, do not specifically lead to thiamine deficiency in the same direct manner as long-term alcohol consumption.