Which of the following would MOST likely cause the lowest number of years of potential life lost (YPLL)?

To determine which option would result in the lowest number of years of potential life lost (YPLL), it's essential to consider the characteristics and epidemiology of each condition.

Cancer often affects individuals later in life, which means that although it can be a leading cause of mortality, the age of onset typically results in fewer years of potential life lost. Individuals may live for many years with cancer or experience it later in their lifetime.

In contrast, trauma, suicide, and congenital heart disease can occur in younger populations, which may lead to higher YPLL. Trauma can lead to sudden deaths in adolescents and young adults, significantly impacting potential life years. Similarly, suicide often affects younger individuals, leading to a substantial loss of years. Congenital heart disease, while it can affect individuals at any age, also has a considerable impact on young lives, particularly if it leads to early mortality.

Therefore, cancer is associated with the least YPLL among the listed choices primarily due to its later onset in life, allowing individuals to live longer even after a cancer diagnosis.